Nanites are particles of multiple sizes and shapes found in Orange Seal's Sealant, available here with the Twist Lock Injection System. When a tire's casing is compromised, those nanites quickly fill any holes, up to a 1/4-inch in diameter, keeping the air in and you rolling. While the nanites do the clogging, latex does the sealing, and both of these ingredients are planet friendly and biodegradable. Because Orange Seal is for the cyclist by the cyclist, weight was a major consideration when developing the mixture. Due to this, Orange Seal can boast that 4oz weighs less than 120 grams. Orange Seal Sealant with Twist Lock Injection System comes in 4- and 8-oz sizes, with the latter being enough for two mountain tires.